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SERUM ANTIOXIDANTS AS PREDICTORS OF ADULT RESPIRAT

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专利名称:SERUM ANTIOXIDANTS AS PREDICTORS OF

ADULT RESPIRATORY DISTRESS SYNDROME

发明人:REPINE, John E.,LEFF, Joanathan A.申请号:EP94912252.0申请日:19940318公开号:EP06674A1公开日:19960103

摘要:At the initial diagnosis of sepsis (6-24 h before the development of ARDS),serum manganese superoxide dismutase (MnSOD) levels and catalase activities areincreased in septic patients who subsequently developed ARDS compared to septicpatients who did not develop ARDS. Increases in MnSOD and catalase may be used topredict the occurrence of ARDS in septic patients with the same sensitivity, specificity andefficiency as parallel assessments of serum lactate dehydrogenase (LDH) and Factor VIIIlevels. Evaluation of serum MnSOD and catalase as well as these other accessible markersfacilitates identification of subsets of patients and allows prospective treatment of septicpatients who are destined to develop ARDS.

申请人:The Webb-Waring Institute for Biomedical Research,THE REGENTS OF THEUNIVERSITY OF COLORADO

地址:Box C-321, 4200 East Ninth Avenue Denver, CO 80262 US,Campus Box 51,University of Colorado Boulder, CO 80309 US

国籍:US,US

代理机构:Goldin, Douglas Michael

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